ItaKiss

Kotoko, from the lowly F-Class, has a crush on Irie, who is the top-ranked student from A-Class. After many years, she collects her courage and confesses to him, only to be bluntly turned down. Irie even goes so far as to say he hates stupid girls.

While walking to school together, Irie tells Kotoko that he doesn't care for her, and when Kotoko is pushed off the train at the wrong station Irie does not help her, saying he hates absent-minded girls even more than stupid ones.

Kotoko falls asleep with a confession letter in her hand. When Irie walks in to tell her it's her turn in the shower, he impulsively decides to read the letter. Later at the school sports festival, Kotoko and Irie end up competing against each other.

Kotoko, Irie and friends visit Waterland. While Irie's getting ice cream, Yuuki ends up sinking in the pool, and Kotoko saves him. Irie overhears about the rescue, rushes back to Yuuki, and is pleased at Kotoko's actions.

The final exams starts next week, and the results decide whether or not the F-class students make it into college. After having received prior assistance from Naoki with her and her friends' schoolwork, much to Irie's annoyance.

It's Valentines Day soon, Irie's mother helps Kotoko make homemade chocolate, but Kotoko fails to give them to Irie. Later on, Naoki goes to take the entrance exam to Tokyo University.

Having missed the entrance exams for Tokyo University, Naoki decides to go with the school's escalator system. After the graduation ceremony, the F and A classes bump into each other during their farewell dinners.

The first day of college has finally arrived and Kotoko finds it hard to forget her kiss with Irie. Just as she thinks she's finally secured a place in Naoki's heart, an obstacle arises in the form of Yuko Matsumoto- smart, beautiful, and talented.

Joining the tennis club turns out to be the worst decision of Kotoko's college life. The grueling practice, the painful injuries and the complete feeling of incompetence would be worth it...if only Naoki would show up to practice!!

Kotoko's father has decided that him and Kotoko have overstayed their welcome, and so the time has finally come for Kotoko to leave the Irie's! How will Kotoko manage? Has she lost her only advantage to winning Naoki's heart!?

Naoki begins thinking about what he wants to do with his life and about the future of the family business. For spring break, Kotoko and Sudou goes to Romance Village to be closer to Naoki and Matsumoto.

Irie tells his father he does not wish to take over his company, instead he wants to become a doctor. Irie's dad has a heart attack after he hears this. When the company employees come to see Irie senior in hospital.

Worried over how to answer Kin, Kotoko talks to her dad about what he thinks about her getting married to Kin. Kotoko's father suggests that they leave Irie's place, Kotoko agrees. Irie brings Chris home to meet his family.

Kotoko feels guilty for having led Kinnosuke on. As she walks in the rain, she encounters Irie, who is holding an umbrella. Irie questions Kotoko about her answer to Kin, she gets upset and replies that it's not Irie's business.

Now married, Kotoko and Naoki head off to Hawaii for their honeymoon. They soon become acquainted with fellow newlyweds Horiuchi Mary (Mari) and Takumi.

Chris is about to return to England, but still harbors strong feelings for Kinnosuke. Feeling sympathetic towards Chris, Kotoko decides to help her in her quest to win Kinnosuke's heart by preparing him a birthday party.

It's Kotoko's first day of learning how to be a nurse and she meets and becomes friends with 4 new people: Kikyou Motoki (who pretends to be a girl but actually is a boy), Shinagawa Marina, Kamogari Keita (a guy), and the lovable Ogura Tomoko.

Kotoko is still learning the tricks and trades of becoming a nurse. But she faints during a practice autopsy which results in Keita saving her. When he lays Kotoko down on the bed, he suddenly felt the urge to kiss her.

Irie starts to ignore Kotoko due to being overly jealous of Keita. During lunch one day, Chris gets burned by oil, and Kinnosuke, refusing to hand her over to anyone else, admits his feelings and devotion and proposes to Chris.

When Kotoko announces to Irie that during the capping ceremony/graduation, the male students in the medical department are to present flowers to the nurses they like, he tells Kotoko that he won't be able to make it to the ceremony because of a meeting.