Nagisa Misumi is an outstanding athlete and daring girl that doesn't take time to study but has a very strong sense of justice. Honoka Yukishiro is an honor-roll student always boasting the best grades in her class. The two are 8th graders at the Verone Junior High School for girls. Nagisa and Honoka each encounter Mepple and Mipple – two mysterious creatures who came down from the sky one night. These two strange creatures grant Nagisa and Honoka the power to transform into superheroes called "Cure Black" and Cure White", and thus the two girls become guardians of planet Earth.
S01:E01 - You Want Us to Transform? No Way!
Nagisa and Honoka are two ordinary middle school students until Mepple and Mipple come from the Field of Light.
S01:E02 - Give Me a Break! a City Targetted by Darkness
Middle school students, Nagisa and Honoka are faced with their second challenge as protectors of light, Cure Black and Cure White.
S01:E03 - Beware of the Cute Student Teacher
In an attempt to get the Prism Stones from Nagisa, dark warrior from Dotsuku Zone, Pisard poses as a new student teacher at Verone Academy.
S01:E04 - A Miracle? the Art Museum Comes to Life!
Nagisa is put in charge of her class’ social studies field trip to the art museum with Honoka as her assistant.
S01:E05 - Serious Trouble! a Desperate Pisard
Pisard returns alone this time, and tries to get the Prism Stones from Honoka.
S01:E06 - A New Darkness! the Bear in the Dangerous Forest
After defeating Pisard, the dark warrior from Dotsuku Zone, Nagisa and Honoka recover a Prism Stone dropped by Pisard.
S01:E07 - A Bitter Lacrosse Battle! a Maiden’s Heart Is So Delicate
Nagisa has a very important lacrosse game, but before the game, she sees Honoka and Fujimura-kun, the soccer player together, and can’t keep her mind on the game.
S01:E08 - The End of Pretty Cure! Isn’t It Too Soon for That!?
Nagisa and Honoka have a big fight when Honoka tries to help Nagisa get to know Fujimura-kun.
S01:E09 - Give Him Back! the Great Mepo Mepo Strategy
Nagisa has a fight with Mepple when Mepple keeps teasing her about Fuji-P, and she threatens not to feed Mepple.
S01:E10 - Honoka Explodes! a Wonderful Birthday
Honoka’s parents come home for Honoka’s birthday
S01:E11 - Save Ryota! Gekidrago Panic
Nagisa takes her little brother, Ryota to the aquarium, so he can write about the fish for his homework.
S01:E12 - The Evil Flower! Poisonny Appears
Nagisa and Honoka meet up with a new evil, dark warrior when Poisonny appears to get the Prism Stones.
S01:E13 - Beware! the Young Transfer Student
A new transfer student named Kiriya Irisawa, comes to the Boys Division.
S01:E14 - Are You Kidding? Pretty Cure Imposters Go Wild
Someone is impersonating Pretty Cure.
S01:E15 - A Really Dangerous Family Vacation
Nagisa goes on a family vacation to what she thought was going to be a lakeside resort hotel.
S01:E16 - Full Throttle Stress! It's Hard Being a Superstar
Nagisa is positive that the Verone Academy superstar, Yuka Odajima dislikes her.
S01:E17 - Capture His Heart! Heart-Throbbing Farm Work
Nagisa gets the chance to be with her heartthrob, Fujimura-kun when Honoka invites her to help out at Kimata’s grandparents’ farm.
S01:E18 - Heart-Throbbing! Mid-Term Tests Are a Love Labyrinth
Nagisa and Honoka are faced with mid-term exams while Nagisa’s shy friend, Seiko decides to confess her love to Kiriya.
S01:E19 - Too Scary! Dotsuku Zone's Final Trump Card
Mipple and Mepple get into a fight, and Nagisa and Honoka can’t seem to get them to make up with each other.
S01:E20 - Which Is the Real One? There Are Two Honokas
Poisonny returns with renewed vigor!
S01:E21 - A Shocking Date! the Truth About Kiriya
Honoka is devastated when Kiriya confesses his true identity to her.
S01:E22 - You're Kidding! Chutaro's Going to Be a Mom!?
Honoka’s dog, Chutaro finds a lost puppy, and takes him under his wing.
S01:E23 - Danger! the Summer Training Camp Nightmare
Training camp turns into a nightmare.
S01:E24 - The Showdown! Pretty Cure vs. Ilkubo
Nagisa, Honoka, the lacrosse team and the science club are still stranded up on the mountains with no power and no telephone to call for help.
S01:E25 - Let's Go to the Field of Light Popo! Us, Too!?
Nagisa and Honoka bring all seven Prism Stones together.
S01:E26 - Goodbye Mepple and Mipple!? No Way!
The Prism Hopish has disappeared from the Field of Light, along with Pretty Cure.
S01:E27 - A New Darkness Closes In! Save the Lost Pollun
When Pretty Cure and Queen defeated Jyaku-King, Queen noticed that Jyaku-King spread some seeds toward the Field of Rainbows.
S01:E28 - Regine Appears! We've Had Enough of the Already
Mipple and Mepple are kept busy, trying to keep Pollun entertained.
S01:E29 - Stormy Summer Festival! the Thunder God Is Super Scary!?
Pollun seems to have the power to foresee the future.
S01:E30 - Explosive! Pretty Cure Rainbow Storm
It seems that the three dark warriors are not only after the Prism Stones, but they have been spawned so they can restore Jyaku-King back to life.
S01:E31 - Did He Really Run Away? Where in the World Is Pollun!?
Pretty Cure learn that the power of the Prism Stones resides inside of Pollun now.
S01:E32 - Cheer Pollun Up! Special Carnival
Nagisa and Honoka take Pollun to the amusement park to try to cheer him up and keep him from getting homesick.
S01:E33 - Get the Victory! Find the Path of Light With Your Heart
Nagisa’s friend and fellow lacrosse player, Shiho has lost confidence in her ability as a lacrosse player.
S01:E34 - Nagisa Breaks Away! the Blazing 'Gachinko' Relay
Nagisa will be running the relay race during the Girls’ Division Sports Festival.
S01:E35 - Is This a Date? Tumultous Happy Birthday
It’s Nagisa’s birthday and she gets the biggest surprise of her life.
S01:E36 - Reach for Freedom! Stone Keeper's Desperate Great Escape
Stone Keeper is left with just the talking cockatoo and two very simple-minded Zakenna butlers to watch over him.
S01:E37 - First Stage Performance!! Don't Lose, Romeo and Juliet
Nagisa and Honoka are chosen to play Romeo and Juliet in their class play for the Verone Festival.
S01:E38 - It Takes Guts! Ryota's Great Errand Strategy
Nagisa is supposed to deliver some important papers to her dad at his office.
S01:E39 - Glittering Tears! Pouring Sweat! a Chaotic Wedding
Nagisa and Honoka’s teacher, Ms. Yoshimi announces that she’s getting married, and the class decides to make her a quilt for a wedding present.
S01:E40 - Invitation to a Dream World!? One-Night Journey Into Darkness
When Honoka’s grandmother goes away for the night, Nagisa spends the night at Honoka’s house.
S01:E41 - We Won't Lose!! Blow the Power of Darkness Away!
Nagisa is in the middle of a championship game with her lacrosse team when Juna, the dark warrior from Dotsuku Zone pulls her away along with Honoka.
S01:E42 - We Are One! Nagisa and Honoka's Powerful Bond
Nagisa and Honoka are separated by the dark warriors from Dotsuku Zone.
S01:E43 - Extremely Shaken Up! My Feelings for Fuji P
Nagisa is torn between helping her friend, Yui to find a present for Fuji P’s birthday, and finding a way to express her own feelings to Fuji P.
S01:E44 - I Couldn't Be Happier!? Nagisa's White Christmas
Nagisa makes chocolate as a Christmas present for Fuji, and she has a chance to give it to him at the Verone Academy student body Christmas party, when he invites her to make a snowman with him. But her chance is ruined again by the dark forces of Dotsu.
S01:E45 - Sing, Sakura Class! the Choir Shows Courage
Nagisa and Honoka’s class is chosen to represent Verone Academy at the Seibu Regional Middle School Singing Competition.
S01:E46 - It's the Pits! Has the Power of the Stones Been Stolen
The dark warriors have figured out that Pollun holds the power of the stones, so they set out to capture him.
S01:E47 - The Most Powerful Warrior Appears! No Way!
Nagisa and Honoka are determined to recover the power of the Prism Stones and the Power of Creation from dark warriors, Belzay, Juna and Regine.
S01:E48 - The Greatest Final Battle! Pretty Cure's Last Day!!
Kiriya whisks Pretty Cure away from danger when the battle for the Power of Creation begins.
S01:E49 - Believe in the Future! Believe in Tomorrow! We Won't Let You Say Goodbye!!
Pretty Cure must battle Jyaku-King who has gotten even more powerful after he gained possession of the Power of Creation.