The 100th Running Man Championship has now begun. Liu participates on behalf of his tribe and arrives to the Tree City gate. Right then, the opening game starts with the announcement saying, "Do not walk, run!" Looking puzzled, Running Man players confront unexpected difficulties.

Running Man players run furiously with unique items given to each of them. Arriving at the path of choice, they continue to run using their special skills. The opening game getting closer to an end, who would be the one to get the final victory?

The opening ceremony for 100th Running Man Championship started. Charming Gold, the host of the game, appeared to announce the grand opening. After introducing each player, the ranking of the previous game appeared on display. Players quarrel over the ranking, making a huge fuss about it.

The first mini game is called "Monster's Mealtime." Everyone becomes a monster in his/her turn, catching all other players. The winner after the intense battle becomes the bell hunter for the next main game.

"The Bell Hunter" is the first individual game, where everyone becomes enemy of one another. Kuga, the winner of the mini game becomes the bell hunter and look for the other players. The other six search for 7 bells, which Kuga has hidden here and there in the stage beforehand. Players decided to cooperate, but no one can be trusted.

Six players look for the bells, using special items or depending on their feelings. They desperately run away from Kuga, who appeared with the ringing sound in the dark. As players get caught one by one, they get suspicious that there is a traitor inside.

Running Man players' first break time. The light of the whole building goes out when everyone was taking a rest in their own room. After a fuss in the dark, Soul Tree outside the window seems brighter than usual. Players start to talk about stories behind Soul Tree and how they get to participate in Running Man Championship.

"B.I.N.G.O." is the next mini game. Players first need to make their own BINGO board with other players' tribal shield. After that, they should find the shields hidden in places of the stage, eliminate competitors and complete two rows of Bingo.

The 2nd individual game is "The Battle of Superpowers." Players wear superpower rings on their watches and use that power for the battle. As they explore one another's superpowers, two alliances are formed among them. Counteracting to Kuga's threatening attacks, Lonky seems to be the most dangerous one!

Lonky eliminates Kuga using his superpower. Popo, who teamed up with Lonky gains confidence and attacks Liu and Miyo by brute force. Right then, Pala, who has been betrayed by Lonky and Popo revives and aims for Popo's shield. Popo seems to overcome the crisis and change momentum of the game.

Kuga mends his gloves after the battle of the superpowers. When he accidentally pricked his finger on the needle, medicbots suddenly appear and make a fuss. Since Kuga drive other players out of his room, they get to think that Kuga is hiding something. They decide to unlock his secret by sneaking into his room. What would Kuga's secret be?

Takji Battle is one of the top 3 sports in Tree City. A tournament using original Takjis made of different sorts of materials. Running Man players throw their own Takjis and show off their unique skills. Who would be the one to flip all other Takjis and win?

All Running Man players are imprisoned for contempt of the Ultimate Takji. The one who solves all riddles of the ultimate prison and escapes win the game. When players escape individual prisons and look for way out, they somehow get imprisoned again one by one. The truth is, there is another hidden mission in this game.

Liu is charged with a secret mission as a reward of winning the Takji battle. As he imprisons all other players again and smoothly escapes, he bumps into Kuga at the top of the tower but who is that player going toward the exit during the encounter of Liu and Kuga?

Running Man players get onto the Express train around Tree City. Excited to get on the train, players get involved with some strange passengers. In the meantime, Pala who missed the train barely managed to get on. When he opened the gate, he found out that someone got murdered!

Running Man players are spotted as key suspects of the murder case! While they verify the spot with Detective Frank, Liu finds a clue to find the real criminal. After collecting the clues at the scene, the real criminal is! Just then, a strange energy swept the crime scene.

The victim who seemed to be dead becomes a zombie and attacks Running Man players! They flee to a different car of the train, but the whole train changed into a zombie world in an instant. They even try to find the vaccine in the very first car, but they cannot hold out any longer. What awaits the Running Man players at the last station?

Liu, Lonky, and Pala is taking a rest in a room together. Pala suddenly brings up an old urban legend about a serial abductor. At that time, Miyo runs along the dark hallway and when the door opens, someone appears behind her. Late at night, a suspicious shadow hovers around Running Man players.

Running Man players disappears one by one, so the remaining players look for the missing ones. When they followed into the hole on the floor, the missing players gathers around in a room. Kuga waits for a chance and draws the abductor into the room to have a fight. But is that move? It can't be him!

Running Man players split into two teams and battle against each other. Players get to choose one team leader from the two, Liu and Kuga. Everyone is playing petty tricks to be in the stronger team, while Pala shows no interest in the team at all.